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References

  1. AGARWAL GP:
    Prevention of atheromatous heart disease. Angiology 36: 485-492, 1985.
  2. AL-AWADI FM, GUMAN KA:
    Studies on the activity of individual plants of an anti-diabetic plant mexture. Acta Diabetol Lat 24:37-42, 1987.
  3. BLITZ JJ, SMITH JW, GERARD JR:
    Aloe Vera Gel in peptic ulcer therapy, preliminary report, J Am Osteopath Assoc 62:731-735, 1963.
  4. BUNYAPRAPHATSARA N, YONGCHAIYUDHA S, RUNGPITARANGSI V, CHOKECHAIJAROENPORN O,
    Antidiabetic activity of Aloe Vera L. juice II. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomed 3:245-248, 1996.
  5. DAVIS RH, DONATO JJ, HARTMAN GM, HAAS RC:
    Anti-inflammatory and wound healing activity of a growth abstance in Aloe Vera. J Am Podiatr Med Assoc 84:77-81, 1994.
  6. DAVIS RH, LEITNER MG, RUSSO JM:
    Topical anti-inflammatory activity of Aloe Vera as measured by ear swelling. J Am Podiatr Med Assoc 77:610-612, 1987.
  7. DAVIS RH, LEITNER MG, RUSSO JM, BYRNE ME:
    Anti-inflammatory activity of Aloe Vera against a spectrum of irritants. J Am Podiatr Med Assoc 79:263-276, 1989.
  8. DAVIS RH, ROSENTHAL KY, CESARIO LR, ROUW GA:
    Processed Aloe Vera administered topically inhibits inflammation. J Am Podiatr Med Assoc 79:395-397,1989.
  9. DAVIS RH, STEWART GJ, BREGMAN PJ:
    Aloe Vera and the inflammed synovial pouch model. J Am Podiatr Med Assoc 82:140-148, 1992.
  10. DIXIT VP, JOSHI S:
    Effect of Aloe Barbadensis and clofibrate on serum lipids in Triniton-induced hyperlipidemia in Presbyter Entellus Entellus Monkeys, Indian J Med Res 78:417-421, 1983.
  11. GALAL EE, KANDIL A, HEGAZY E, EL GHOROURY M, GOBRAN W:
    Aloe Vera and gastrointestinal ulceration, J Drug Res Egypt 7:73-77, 1975.
  12. GUPTA MB, NATH R, GUPTA GP, BHARGAVA KP:
    Antiulcer activity of some plant triterpenoids, Indian J Med Res 73:649-652, 1981.
  13. HIKINO H, HAYASHI T:
    Hypoglycemic polysaccharides extraction from Aloe species, Jpn Kokai Tokkyo Koho, JP 60,214,741, 28 Oct 1985.
  14. HIKINO H, TAKAHASHI M, MURAKAMI M, KONNO C, MIRIN Y, KARIKURA M, HAYASHI T:
    Isolation and hypoglycemic activity of arborans A and B, glycans of Aloe arborescens var, natalensis leaves, Int J Crude Drug Res 24:183-186, 1986.
  15. HUTTER JA, SALMAN M, STAVINOHA WB, SATSANGI N, WILLIAMS RF, STREEPER RT, WEINTRAUB ST:
    Anti-inflammatory C-glucosyl chromone from Aloe barbadensis, J Natural Prod 59:541-543, 1996.
  16. JOSHI S. DIXIT VP:
    Hypolipidemia effect of Aloe barbadensis (Aloe fraction I) in cholesterol-fed rats. I. Lipid and lipoprotein metabolism, Proc Nat Acad Sci India, Sect B (Biol Sci) 56:339-342, 1986.
  17. KADYROV MA, SHARKIROV DSH:
    treatment of fractures by adaptogens under experimental conditions. Eksp Khu Anesteziol 12:50-52, 1967.
  18. KALINICHEVA NV, SHAPKINA AV:
    Stimulation of the regeneration of the insular epithelium of the pancreas by some drugs. Tr Leningr Sanit-Gig Med Inst 112:58-64, 1976.
  19. KANDIL A, GOBRAN W:
    Protection of gastric mucosa by Aloe Vera, J Drug Res Egypt 11:191-196, 1979.
  20. SAVITSKII VI:
    The effect of tissue preparations on the biochemical processes of the body, In: The use of tissue preparations in animal husbandry and veterinary medicine, Urozhai, Kiev ():31-41,1966. From: Ref Zh Otd Vyp Farmakol Khimioter Sredstva Toksikol, No. 6, 54638, 1967.
  21. SHAMATOV NM:
    Effect of Aloe extract on the accumulation of Clcium45 and Phosphorus32 in normal and calloused bones, Uckenye Zapiski 2-01 Moskov Med Inst 6:67-69, 1957. Ref. Zh Khim, Biol Khim, 1959, Abstract #3313.
  22. SOLOV'EVA VP:
    Effect of Aloe extract on some biochemical indicators of normal and sick persons. Vrachebnoe Delo ():93-98, 1958.
  23. SUGA T, HIRATA T:
    The efficacy of the Aloe plants chemical constituents and biological activities. Cosmet & Toil 98:105-108, 1983.
  24. VAZQUEZ B, AVILA G, SEGURA D, ESCALANTE B:
    Anti-inflammatory activity of extracts from Aloe Vera Gel. J Ethnopharmacol 55:69-75, 1996.
  25. YAGI A, HARADA N, SHIMOMURA K, NISHIOKA I:
    Bradykinin-Degradin glycoprotein in Aloe arborescens var. Natalensis. Planta Med 53:19-21, 1987.
  26. YAGI A, SHIBATA S, NISHIOKA I, IWADARE S, ISHIDA Y:
    Cardiac stimulant action of constituents of Aloe saponaria. J Pharm Sci 71:739-741, 1982.
  27. YONGCHAIYUDHA S, RUNGPITARANGSI V, BUNYAPRAPHATSARA N, CHOKECHAIJAROENPORN 0:
    Antidiabetic activity of Aloe Vera L. Juice I. Clinical trial in new cases of diabetes mellitus. Phytomed 3:241-243, 1996.

THE HISTORY OF ALOE VERA TOTAL PROCESS

Aloe Vera is a semi-tropical plant that grows on hot areas, whose healing properties are widely known around the world.

Aloe Vera is relationed with Lileaceas Family. Our Aloe Vera leaves have an average of high from 50 cms. to 80 cms. Everyplant of Aloe Vera contains 24 leaves of average and harvesting between 8 and 12 leaves every three months.

Aloe Vera between its ingredients is a substance called Aloine (yellow color liquid) and Aloe Gel, a gelatinuos substance, semi-solid and no color that was stabilized. Some clinical cases showed that Aloe Vera Gel contains amino-acids, vitamines, minerals,enzimas, polysaccharides and others substances which they were used as bases to manufacture nutritive drinks, as healing agent and as cosmetics mousturizing. This caused several detailed studies about Aloe´s components.

Aloe success as an ingredient to nutritive foods, cosmetics, healings and analgesics is to the stabilization procedures that not allow its decomposition fase.

Nowadays, The International Aloe Science Council who is charged to certificate the purity of Aloe Vera, has established standars to Aloe Vera leaves and Aloe Vera Gel.

STANDARDS ESTABLISHED FOR ALOE LEAVE & GEL

ALOE VERA GELALOE VERA LEAF
TEST AVERAGETEST AVERAGE
Ph3.8Ph3.9
Solids0.88Solids1.2
Calcium241.3 mg/lCalcium mg/l565.1
Magnesium58.4 mg/l Magnesium mg/l 82.5
Malic Acid2028.7 mg/l Malic Acid mg/l 4287

The MPS Benefits
By Dr. Ivan E. Danhof

When alcohols are added to Aloe solutions, about 20 to 25% of the total solids come out of the solution, or we say "precipitate". This is MPS. It consist of polysaccharides, glycoprotein and salts of organic acids. Depending upon the origin of the Aloe leaves, the harvesting conditions and leaf processing. The polysaccharides represent about one-half two thirds of the MPS or about 10 to 15% of total solids. in Aloe from some geographical locations, the percentage of Polysaccharides may be even higher.

These polysaccharides consist of simple sugar molecules. In Aloe, the sugars molecules are comprised of glucose (also called blood sugar or dextrose) and mannose, which are linked together in short, long or very long unbranched chains. As a rule, if the sugar chain contains 6 or more hexoses, and a molecular weight of 1,000 daltons or more, they are considered polysaccharides (poly=many, saccharide=sugar). Other components including anthraquinones (laxative, antiviral), minerals, (calcium, mangnesium,etc.) may offer protective and potentially preventive or curative activities for human kind.

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The Total Process Difference

Hand-Filleted Gel VS. Total Process with Pulp

Whole Leaf VS. Total Process with No Pulp

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Potential Benefits of Orally-Ingested Aloe Juice

Scientific evidence is accruing in both animal and human studies which suggest increasing credibility for the benefits of ingested aloe juice for a number of conditions:

1. Cardiovascular System.
A. Aloe constituents include a salt, calcium isocitrate, which in animal studies possesses actions similar to digitalis (26) and increases the force of cardiac contraction.

B. Other constituents have been found to lower the cholesterol level (10,11) as well as the triglyceride level (4, 10, 16). A large clinical study suggested that extant atheromatous cardiovascular disease could be reversed by the ingestion of aloe (1).

2. Gastrointestinal System.
A. Gastrointestinal ulcers showed accelerated healing rates (11) in animal models, and pretreatment with aloe prior to inducing ulcers in animal models suggested a high degree of ulceroprotection (19). The triterpene, lupeol, documented as an aloe constituent has been implicated as a possible ulceroprotective agent (12, 23). An uncontrolled human study in which the aloe/petrolatum material was ingested was interpreted by the authors as ulceroprotective (3).

B. Evidence has been gathered in animals in which experimental cirrhosis of the liver that has been induced which suggests that the administration of aloe provided protection of the liver cells against the cirrhosis-inducing agents (20, 22).

3. Skeletal System.
A.
The most prevalent use of orally-ingested aloe beverages anecdotally has been for arthritis and other inflammatory conditions, experimental evidence corroborating anti-inflammatory activity of several aloe constituents in various animal models cab be found reported in the scientific literature (5, 6, 7, 8, 9 15, 24, 25).

B. Acceleration of incorporation of calcium and phosphorus in callus formation in sites of experimental bone fractures has been demonstrated in animal models (17, 21).

4. Endocrine System. Studies in both type 1 and type 2 diabetes mellitus in animal models reflect hypoglycemic activity of various aloe constituents (2, 13, 14). Other investigations suggest that aloe may contain constituents which have the capability of stimulating regeneration of cells in the islets of langerhans including the beta cells, the site of insulin synthesis and release (18). Recently published studies in humans given aloe preparations showed significant, long-lasting blood glucose control properties (4, 27).

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